Cargando…
Ligand effects on phase separation of multivalent macromolecules
Biomolecular condensates enable spatial and temporal control over cellular processes by concentrating biomolecules into nonstoichiometric assemblies. Many condensates form via reversible phase transitions of condensate-specific multivalent macromolecules known as scaffolds. Phase transitions of scaf...
Autores principales: | Ruff, Kiersten M., Dar, Furqan, Pappu, Rohit V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958451/ https://www.ncbi.nlm.nih.gov/pubmed/33653957 http://dx.doi.org/10.1073/pnas.2017184118 |
Ejemplares similares
-
Polyphasic linkage and the impact of ligand binding on the regulation of biomolecular condensates
por: Ruff, Kiersten M., et al.
Publicado: (2021) -
LASSI: A lattice model for simulating phase transitions of multivalent proteins
por: Choi, Jeong-Mo, et al.
Publicado: (2019) -
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
por: Harmon, Tyler S, et al.
Publicado: (2017) -
Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins
por: Zeng, Xiangze, et al.
Publicado: (2022) -
Connecting sequence features within the disordered C-terminal linker of Bacillus subtilis FtsZ to functions and bacterial cell division
por: Shinn, Min Kyung, et al.
Publicado: (2022)