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Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development

Despite the critical role of Plasmodium sporozoites in malaria transmission, we still know little about the mechanisms underlying their development in mosquitoes. Here, we use single-cell RNA sequencing to characterize the gene expression profiles of 16,038 Plasmodium berghei sporozoites isolated th...

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Detalles Bibliográficos
Autores principales: Bogale, Haikel N., Pascini, Tales V., Kanatani, Sachie, Sá, Juliana M., Wellems, Thomas E., Sinnis, Photini, Vega-Rodríguez, Joel, Serre, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958459/
https://www.ncbi.nlm.nih.gov/pubmed/33653959
http://dx.doi.org/10.1073/pnas.2023438118