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Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development
Despite the critical role of Plasmodium sporozoites in malaria transmission, we still know little about the mechanisms underlying their development in mosquitoes. Here, we use single-cell RNA sequencing to characterize the gene expression profiles of 16,038 Plasmodium berghei sporozoites isolated th...
Autores principales: | Bogale, Haikel N., Pascini, Tales V., Kanatani, Sachie, Sá, Juliana M., Wellems, Thomas E., Sinnis, Photini, Vega-Rodríguez, Joel, Serre, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958459/ https://www.ncbi.nlm.nih.gov/pubmed/33653959 http://dx.doi.org/10.1073/pnas.2023438118 |
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