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Molecular and Pharmacological Characterization of the Interaction between Human Geranylgeranyltransferase Type I and Ras-Related Protein Rap1B

Geranylgeranyltransferase type-I (GGTase-I) represents an important drug target since it contributes to the function of many proteins that are involved in tumor development and metastasis. This led to the development of GGTase-I inhibitors as anti-cancer drugs blocking the protein function and membr...

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Detalles Bibliográficos
Autores principales: Hinz, Sonja, Jung, Dominik, Hauert, Dorota, Bachmann, Hagen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958859/
https://www.ncbi.nlm.nih.gov/pubmed/33801503
http://dx.doi.org/10.3390/ijms22052501