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Pharmacological inhibition of mTORC1 activity protects against inflammation-induced apoptosis of nucleus pulposus cells

Lumbar disc herniation is a common disease characterized by the degeneration of intervertebral discs (IVDs), accompanied by imbalance of metabolic and inflammatory homeostasis. Current studies establish that IVD degeneration is induced by increased apoptosis of nucleus pulposus (NP) cells. However,...

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Detalles Bibliográficos
Autores principales: Chen, Rigao, Yang, Fei, Wang, Yong, Wang, Xinling, Fan, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959168/
https://www.ncbi.nlm.nih.gov/pubmed/33729389
http://dx.doi.org/10.1590/1414-431X202010185