A Novel 1,8-Naphthyridine-2-Carboxamide Derivative Attenuates Inflammatory Responses and Cell Migration in LPS-Treated BV2 Cells via the Suppression of ROS Generation and TLR4/Myd88/NF-κB Signaling Pathway

Novel 1,8-naphthyridine-2-carboxamide derivatives with various substituents (HSR2101-HSR2113) were synthesized and evaluated for their effects on the production of pro-inflammatory mediators and cell migration in lipopolysaccharide (LPS)-treated BV2 microglial cells. Among the tested compounds, HSR2...

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Detalles Bibliográficos
Autores principales: Nguyen, Phuong Linh, Bui, Bich Phuong, Lee, Heesoon, Cho, Jungsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959294/
https://www.ncbi.nlm.nih.gov/pubmed/33802409
http://dx.doi.org/10.3390/ijms22052527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959294/
https://www.ncbi.nlm.nih.gov/pubmed/33802409
http://dx.doi.org/10.3390/ijms22052527

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