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Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure

Control of the neglected tropical disease schistosomiasis relies almost entirely on praziquantel (PZQ) monotherapy. How PZQ clears parasite infections remains poorly understood. Many studies have examined the effects of PZQ on worms cultured in vitro, observing outcomes such as muscle contraction. H...

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Detalles Bibliográficos
Autores principales: McCusker, Paul, Rohr, Claudia M., Chan, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959349/
https://www.ncbi.nlm.nih.gov/pubmed/33657133
http://dx.doi.org/10.1371/journal.pntd.0009200