A high-affinity RBD-targeting nanobody improves fusion partner’s potency against SARS-CoV-2

A key step to the SARS-CoV-2 infection is the attachment of its Spike receptor-binding domain (S RBD) to the host receptor ACE2. Considerable research has been devoted to the development of neutralizing antibodies, including llama-derived single-chain nanobodies, to target the receptor-binding motif...

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Detalles Bibliográficos
Autores principales: Yao, Hebang, Cai, Hongmin, Li, Tingting, Zhou, Bingjie, Qin, Wenming, Lavillette, Dimitri, Li, Dianfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959386/
https://www.ncbi.nlm.nih.gov/pubmed/33657135
http://dx.doi.org/10.1371/journal.ppat.1009328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959386/
https://www.ncbi.nlm.nih.gov/pubmed/33657135
http://dx.doi.org/10.1371/journal.ppat.1009328

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