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A high-affinity RBD-targeting nanobody improves fusion partner’s potency against SARS-CoV-2
A key step to the SARS-CoV-2 infection is the attachment of its Spike receptor-binding domain (S RBD) to the host receptor ACE2. Considerable research has been devoted to the development of neutralizing antibodies, including llama-derived single-chain nanobodies, to target the receptor-binding motif...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959386/ https://www.ncbi.nlm.nih.gov/pubmed/33657135 http://dx.doi.org/10.1371/journal.ppat.1009328 |