Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype

The extracellular matrix (ECM) plays a key role in the viability and survival of implanted human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). We hypothesized that coating of three-dimensional (3D) cardiac tissue-derived hiPSC-CMs with the ECM protein fibronectin (FN) would impro...

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Detalles Bibliográficos
Autores principales: Yokoyama, Junya, Miyagawa, Shigeru, Akagi, Takami, Akashi, Mitsuru, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959395/
https://www.ncbi.nlm.nih.gov/pubmed/33720933
http://dx.doi.org/10.1371/journal.pone.0245571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959395/
https://www.ncbi.nlm.nih.gov/pubmed/33720933
http://dx.doi.org/10.1371/journal.pone.0245571

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