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B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency
Conversion of human pluripotent stem cells from primed to naïve state is accompanied by altered transcriptome and methylome, but glycosphingolipid (GSL) profiles in naïve human embryonic stem cells (hESCs) have not been systematically characterized. Here we showed a switch from globo-(SSEA-3, SSEA-4...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959494/ https://www.ncbi.nlm.nih.gov/pubmed/33087559 http://dx.doi.org/10.1073/pnas.2003155117 |