Cargando…

B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency

Conversion of human pluripotent stem cells from primed to naïve state is accompanied by altered transcriptome and methylome, but glycosphingolipid (GSL) profiles in naïve human embryonic stem cells (hESCs) have not been systematically characterized. Here we showed a switch from globo-(SSEA-3, SSEA-4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Ruey-Jen, Kuo, Ming-Wei, Yang, Bei-Chia, Tsai, Hsiu-Hui, Chen, Kowa, Huang, Jing-Rong, Lee, Yun-Shien, Yu, Alice L., Yu, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959494/ https://www.ncbi.nlm.nih.gov/pubmed/33087559 http://dx.doi.org/10.1073/pnas.2003155117

Ejemplares similares

Nucleotide sugar profiles throughout development in wildtype and galt knockout zebrafish
por: Haskovic, Minela, et al.
Publicado: (2020)

High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma
por: Kuo, Huan-Hsien, et al.
Publicado: (2017)

Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition
por: Quan, Yujun, et al.
Publicado: (2022)

ZIC3 Controls the Transition from Naive to Primed Pluripotency
por: Yang, Shen-Hsi, et al.
Publicado: (2019)

Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigs
por: Shim, Joohyun, et al.
Publicado: (2021)

Two Hydroxyproline Galactosyltransferases, GALT5 and GALT2, Function in Arabinogalactan-Protein Glycosylation, Growth and Development in Arabidopsis
por: Basu, Debarati, et al.
Publicado: (2015)

RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells
por: Altshuler, Anna, et al.
Publicado: (2018)

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation
por: Patani, Hemalvi, et al.
Publicado: (2020)

Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout
por: Yang, Bin, et al.
Publicado: (2020)

Selective Generation of Gut Tropic T Cells in Gut-associated Lymphoid Tissue (GALT): Requirement for GALT Dendritic Cells and Adjuvant
por: Johansson-Lindbom, Bengt, et al.
Publicado: (2003)

C1GALT1 in health and disease
por: Sun, Xiaojie, et al.
Publicado: (2021)

Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency
por: Bredenkamp, Nicholas, et al.
Publicado: (2019)

YAP Induces Human Naive Pluripotency
por: Qin, Han, et al.
Publicado: (2016)

Expression and Impact of C1GalT1 in Cancer Development and Progression
por: Wan, Yangu, et al.
Publicado: (2021)

Resetting Human Naïve Pluripotency
por: Xiao, Jifang, et al.
Publicado: (2016)

High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer
por: Liao, Yu-Mei, et al.
Publicado: (2021)

Ovarian function in girls and women with GALT-deficiency galactosemia
por: Fridovich-Keil, Judith L., et al.
Publicado: (2010)

Update on the role of C1GALT1 in cancer
por: Xia, Tong, et al.
Publicado: (2022)

Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
por: Chen, Po-Da, et al.
Publicado: (2023)

The Current State of Naïve Human Pluripotency
por: Dodsworth, Benjamin T., et al.
Publicado: (2015)

Taking the RISC of exiting naïve pluripotency
por: Guallar, Diana, et al.
Publicado: (2016)

Compound heterozygosity with a novel S222N GALT mutation leads to atypical galactosemia with loss of GALT activity in erythrocytes but little evidence of clinical disease
por: Cocanougher, Benjamin, et al.
Publicado: (2015)

Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency
por: Lackner, Andreas, et al.
Publicado: (2021)

C1GALT1 expression predicts a favorable prognosis and suppresses malignant phenotypes via TrkA signaling in neuroblastoma
por: Lin, Neng-Yu, et al.
Publicado: (2022)

The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells
por: Bredenkamp, Nicholas, et al.
Publicado: (2019)

Naïve pluripotency is associated with global DNA hypomethylation
por: Leitch, Harry G., et al.
Publicado: (2013)

Manipulating the Mediator complex to induce naïve pluripotency
por: Lynch, Cian J., et al.
Publicado: (2020)

Plakoglobin is a mechanoresponsive regulator of naive pluripotency
por: Kohler, Timo N., et al.
Publicado: (2023)

Suppression of YAP safeguards human naïve pluripotency
por: Dattani, Anish, et al.
Publicado: (2022)

Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency
por: Kalkan, Tüzer, et al.
Publicado: (2019)

Discordance between chromatin accessibility and transcriptional activity during the human primed-to-naïve pluripotency transition process
por: Tu, Zhifen, et al.
Publicado: (2023)

b3galt6 Knock-Out Zebrafish Recapitulate β3GalT6-Deficiency Disorders in Human and Reveal a Trisaccharide Proteoglycan Linkage Region
por: Delbaere, Sarah, et al.
Publicado: (2020)

Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells
por: Rohani, Leili, et al.
Publicado: (2020)

Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition
por: Wu, Yi, et al.
Publicado: (2019)

RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription
por: Abuhashem, Abderhman, et al.
Publicado: (2022)

Sialylation of vasorin by ST3Gal1 facilitates TGF‐β1‐mediated tumor angiogenesis and progression
por: Yeo, Hui Ling, et al.
Publicado: (2019)

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
por: Osnato, Anna, et al.
Publicado: (2021)

Severe Peripheral Joint Laxity is a Distinctive Clinical Feature of Spondylodysplastic-Ehlers-Danlos Syndrome (EDS)-B4GALT7 and Spondylodysplastic-EDS-B3GALT6
por: Caraffi, Stefano Giuseppe, et al.
Publicado: (2019)

Mapping the route from naive pluripotency to lineage specification
por: Kalkan, Tüzer, et al.
Publicado: (2014)

Molecular Criteria for Defining the Naive Human Pluripotent State
por: Theunissen, Thorold W., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k6uaeiorck50qmacuf9122ecup