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Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae
The extracellular polysaccharide capsule of Klebsiella pneumoniae resists penetration by antimicrobials and protects the bacteria from the innate immune system. Host antimicrobial peptides are inactivated by the capsule as it impedes their penetration to the bacterial membrane. While the capsule seq...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959497/ https://www.ncbi.nlm.nih.gov/pubmed/33087568 http://dx.doi.org/10.1073/pnas.2007036117 |