Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography

Desmosomes are cell–cell junctions that link tissue cells experiencing intense mechanical stress. Although the structure of the desmosomal cadherins is known, the desmosome architecture—which is essential for mediating numerous functions—remains elusive. Here, we recorded cryo-electron tomograms (cr...

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Detalles Bibliográficos
Autores principales: Sikora, Mateusz, Ermel, Utz H., Seybold, Anna, Kunz, Michael, Calloni, Giulia, Reitz, Julian, Vabulas, R. Martin, Hummer, Gerhard, Frangakis, Achilleas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959525/
https://www.ncbi.nlm.nih.gov/pubmed/33067392
http://dx.doi.org/10.1073/pnas.2004563117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959525/
https://www.ncbi.nlm.nih.gov/pubmed/33067392
http://dx.doi.org/10.1073/pnas.2004563117

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