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Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C

Human rhinoviruses (RVs) are positive-strand RNA viruses that cause respiratory tract disease in children and adults. Here we show that the innate immune signaling protein STING is required for efficient replication of members of two distinct RV species, RV-A and RV-C. The host factor activity of ST...

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Detalles Bibliográficos
Autores principales: McKnight, Kevin L., Swanson, Karen V., Austgen, Kathryn, Richards, Cindy, Mitchell, Jonathan K., McGivern, David R., Fritch, Ethan, Johnson, John, Remlinger, Katja, Magid-Slav, Michal, Kapustina, Maryna, You, Shihyun, Lemon, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959528/
https://www.ncbi.nlm.nih.gov/pubmed/33060297
http://dx.doi.org/10.1073/pnas.2014940117