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Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C
Human rhinoviruses (RVs) are positive-strand RNA viruses that cause respiratory tract disease in children and adults. Here we show that the innate immune signaling protein STING is required for efficient replication of members of two distinct RV species, RV-A and RV-C. The host factor activity of ST...
Autores principales: | McKnight, Kevin L., Swanson, Karen V., Austgen, Kathryn, Richards, Cindy, Mitchell, Jonathan K., McGivern, David R., Fritch, Ethan, Johnson, John, Remlinger, Katja, Magid-Slav, Michal, Kapustina, Maryna, You, Shihyun, Lemon, Stanley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959528/ https://www.ncbi.nlm.nih.gov/pubmed/33060297 http://dx.doi.org/10.1073/pnas.2014940117 |
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