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Liquid drop of DNA libraries reveals total genome information

Conventional “bulk” PCR often yields inefficient and nonuniform amplification of complex templates in DNA libraries, introducing unwanted biases. Amplification of single DNA molecules encapsulated in a myriad of emulsion droplets (emulsion PCR, ePCR) allows the mitigation of this problem. Different...

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Detalles Bibliográficos
Autores principales: Terekhov, Stanislav S., Eliseev, Igor E., Ovchinnikova, Leyla A., Kabilov, Marsel R., Prjibelski, Andrey D., Tupikin, Alexey E., Smirnov, Ivan V., Belogurov, Alexey A., Severinov, Konstantin V., Lomakin, Yakov A., Altman, Sidney, Gabibov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959537/
https://www.ncbi.nlm.nih.gov/pubmed/33087570
http://dx.doi.org/10.1073/pnas.2017138117