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Liquid drop of DNA libraries reveals total genome information
Conventional “bulk” PCR often yields inefficient and nonuniform amplification of complex templates in DNA libraries, introducing unwanted biases. Amplification of single DNA molecules encapsulated in a myriad of emulsion droplets (emulsion PCR, ePCR) allows the mitigation of this problem. Different...
Autores principales: | Terekhov, Stanislav S., Eliseev, Igor E., Ovchinnikova, Leyla A., Kabilov, Marsel R., Prjibelski, Andrey D., Tupikin, Alexey E., Smirnov, Ivan V., Belogurov, Alexey A., Severinov, Konstantin V., Lomakin, Yakov A., Altman, Sidney, Gabibov, Alexander G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959537/ https://www.ncbi.nlm.nih.gov/pubmed/33087570 http://dx.doi.org/10.1073/pnas.2017138117 |
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