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Patient-Derived Nasopharyngeal Cancer Organoids for Disease Modeling and Radiation Dose Optimization

Effective radiation treatment (RT) for recurrent nasopharyngeal cancers (NPC), featuring an intrinsic hypoxic sub-volume, remains a clinical challenge. Lack of disease‐specific in-vitro models of NPC, together with difficulties in establishing patient derived xenograft (PDX) models, have further hin...

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Detalles Bibliográficos
Autores principales: Lucky, Sasidharan Swarnalatha, Law, Martin, Lui, Ming Hong, Mong, Jamie, Shi, Junli, Yu, Sidney, Yoon, Do Kun, Djeng, Shih Kien, Wang, Jiguang, Lim, Chwee Ming, Tan, Min Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959730/
https://www.ncbi.nlm.nih.gov/pubmed/33732646
http://dx.doi.org/10.3389/fonc.2021.622244