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Dysregulation of miR-138-5p/RPS6KA1-AP2M1 Is Associated With Poor Prognosis in AML

Acute myeloid leukemia (AML) is a malignant disease of hematopoietic stem/progenitor cells, and most AML patients are in a severe state. Internal tandem duplication mutations in FLT3 gene (FLT3-ITD) detected in AML stem cells account for 20–30 percent of AML patients. In this study, we attempted to...

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Detalles Bibliográficos
Autores principales: Yu, Dong-Hu, Chen, Chen, Liu, Xiao-Ping, Yao, Jie, Li, Sheng, Ruan, Xiao-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959750/
https://www.ncbi.nlm.nih.gov/pubmed/33732707
http://dx.doi.org/10.3389/fcell.2021.641629