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The Role of CXCL13 in Antibody Responses to HIV-1 Infection and Vaccination

CXCL13 signals through the G protein-coupled chemokine receptor CXCR5 to drive development of secondary lymphoid tissue as well as B cell and Tfh cell trafficking to germinal centers (GC), which leads to the differentiation of B cells to plasma cells and memory B cells. CXCL13 has been proposed as a...

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Detalles Bibliográficos
Autores principales: Bekele Feyissa, Yonas, Chiodi, Francesca, Sui, Yongjun, Berzofsky, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959754/
https://www.ncbi.nlm.nih.gov/pubmed/33732259
http://dx.doi.org/10.3389/fimmu.2021.638872