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Engineered Bacteria of MG1363-pMG36e-GLP-1 Attenuated Obesity-Induced by High Fat Diet in Mice

BACKGROUND: Although gut hormone glucagon-like peptide 1 (GLP-1) has been widely used for treating diabetes, the extremely short half-life greatly limits its application. The purpose of this study is to explore the effects of an engineered bacteria with expression of GLP-1 on obese mice induced by h...

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Detalles Bibliográficos
Autores principales: Wang, Lingfang, Chen, Tingtao, Wang, Huan, Wu, Xiaoli, Cao, Qing, Wen, Ke, Deng, Ke-Yu, Xin, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959774/
https://www.ncbi.nlm.nih.gov/pubmed/33732656
http://dx.doi.org/10.3389/fcimb.2021.595575