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Engineered Bacteria of MG1363-pMG36e-GLP-1 Attenuated Obesity-Induced by High Fat Diet in Mice
BACKGROUND: Although gut hormone glucagon-like peptide 1 (GLP-1) has been widely used for treating diabetes, the extremely short half-life greatly limits its application. The purpose of this study is to explore the effects of an engineered bacteria with expression of GLP-1 on obese mice induced by h...
Autores principales: | Wang, Lingfang, Chen, Tingtao, Wang, Huan, Wu, Xiaoli, Cao, Qing, Wen, Ke, Deng, Ke-Yu, Xin, Hongbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959774/ https://www.ncbi.nlm.nih.gov/pubmed/33732656 http://dx.doi.org/10.3389/fcimb.2021.595575 |
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