Cargando…

Deoxypodophyllotoxin Inhibits Non-Small Cell Lung Cancer Cell Growth by Reducing HIF-1α-Mediated Glycolysis

Cancer cell proliferation is a metabolically demanding process that requires high rate of glycolysis to support anabolic growth. Deoxypodophyllotoxin (DPT) is a natural flavonolignan with various pharmacological activities, including antitumor effect. However, whether DPT affects the metabolic repro...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yuping, Liu, Lingling, Sun, Jinghui, Wang, Shu, Yang, Zhongyuan, Li, Honghui, Huang, Na, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959795/
https://www.ncbi.nlm.nih.gov/pubmed/33732648
http://dx.doi.org/10.3389/fonc.2021.629543