Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis

Peroxisome proliferator-activated receptor (PPAR)-δ is a nuclear receptor that functions to maintain metabolic homeostasis, regulate cell growth, and limit the development of excessive inflammation during immune responses. Previously, we reported that PPAR-δ-deficient mice develop a more severe clin...

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Detalles Bibliográficos
Autores principales: Doroshenko, Ellinore R., Drohomyrecky, Paulina C., Gower, Annette, Whetstone, Heather, Cahill, Lindsay S., Ganguly, Milan, Spring, Shoshana, Yi, Tae Joon, Sled, John G., Dunn, Shannon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959796/
https://www.ncbi.nlm.nih.gov/pubmed/33732230
http://dx.doi.org/10.3389/fimmu.2021.570425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959796/
https://www.ncbi.nlm.nih.gov/pubmed/33732230
http://dx.doi.org/10.3389/fimmu.2021.570425

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