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Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis
Peroxisome proliferator-activated receptor (PPAR)-δ is a nuclear receptor that functions to maintain metabolic homeostasis, regulate cell growth, and limit the development of excessive inflammation during immune responses. Previously, we reported that PPAR-δ-deficient mice develop a more severe clin...
Autores principales: | Doroshenko, Ellinore R., Drohomyrecky, Paulina C., Gower, Annette, Whetstone, Heather, Cahill, Lindsay S., Ganguly, Milan, Spring, Shoshana, Yi, Tae Joon, Sled, John G., Dunn, Shannon E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959796/ https://www.ncbi.nlm.nih.gov/pubmed/33732230 http://dx.doi.org/10.3389/fimmu.2021.570425 |
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