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Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases

Several clinical and experimental studies have documented a compelling and critical role for the full-length matrix metalloproteinase-2 (FL-MMP-2) in ischemic renal injury, progressive renal fibrosis, and diabetic nephropathy. A novel N-terminal truncated isoform of MMP-2 (NTT-MMP-2) was recently di...

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Detalles Bibliográficos
Autores principales: Cruz, Juliana de Oliveira, Silva, Alessandra O., Ribeiro, Jessyca M., Luizon, Marcelo R., Ceron, Carla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959838/
https://www.ncbi.nlm.nih.gov/pubmed/33732288
http://dx.doi.org/10.3389/fgene.2021.637148