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Inhibition of miRNA-155 Alleviates High Glucose-Induced Podocyte Inflammation by Targeting SIRT1 in Diabetic Mice

OBJECTIVE: Microinflammation plays a crucial role in podocyte dysfunction in diabetic nephropathy, but its regulatory mechanism is still unclear. This study is aimed at discussing the mechanisms underlying the effect of miRNA-155 on podocyte injury to determine its potential as a therapeutic target....

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Detalles Bibliográficos
Autores principales: Wang, Xiaolei, Gao, Yanbin, Yi, Wenming, Qiao, Yu, Hu, Hao, Wang, Ying, Hu, Yan, Wu, Shuxin, Sun, Hongfeng, Zhang, Taojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960039/
https://www.ncbi.nlm.nih.gov/pubmed/33748285
http://dx.doi.org/10.1155/2021/5597394