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Baclofen and naltrexone, but not N-acetylcysteine, affect voluntary alcohol drinking in rats regardless of individual levels of alcohol intake

In humans, there is profound individual variation in the risk of alcohol use disorder (AUD). Because GABA, opioid and glutamate neurotransmission have been implicated in AUD, functional differences in these neural systems may underlie the individual vulnerability to AUD. We therefore determined the...

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Detalles Bibliográficos
Autores principales: Minnaard, A. Maryse, Ramakers, Geert M.J., Vanderschuren, Louk J.M.J., Lesscher, Heidi M.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams and Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960148/
https://www.ncbi.nlm.nih.gov/pubmed/33315615
http://dx.doi.org/10.1097/FBP.0000000000000615