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Cell-penetrating peptides enhance the transduction of adeno-associated virus serotype 9 in the central nervous system
Recombinant adeno-associated viruses (rAAVs) have been widely used in the gene therapy field for decades. However, because of the challenge of effectively delivering rAAV vectors through the blood-brain barrier (BBB), their applications for treatment of central nervous system (CNS) diseases are quit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960505/ https://www.ncbi.nlm.nih.gov/pubmed/33768127 http://dx.doi.org/10.1016/j.omtm.2021.02.019 |