Cell-penetrating peptides enhance the transduction of adeno-associated virus serotype 9 in the central nervous system

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Recombinant adeno-associated viruses (rAAVs) have been widely used in the gene therapy field for decades. However, because of the challenge of effectively delivering rAAV vectors through the blood-brain barrier (BBB), their applications for treatment of central nervous system (CNS) diseases are quit...

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Detalles Bibliográficos
Autores principales: Meng, Yuan, Sun, Dong, Qin, Yiyan, Dong, Xiaoyi, Luo, Guangzuo, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960505/
https://www.ncbi.nlm.nih.gov/pubmed/33768127
http://dx.doi.org/10.1016/j.omtm.2021.02.019

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