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Transcriptional mediators of treatment resistance in lethal prostate cancer
Metastatic castration-resistant prostate cancer is typically lethal, exhibiting intrinsic or acquired resistance to second-generation androgen-targeting therapies and minimal response to immune checkpoint inhibitors(1). Cellular programs driving resistance in both cancer and immune cells remain poor...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960507/ https://www.ncbi.nlm.nih.gov/pubmed/33664492 http://dx.doi.org/10.1038/s41591-021-01244-6 |