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USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

DNA–protein cross-links (DPCs) are toxic DNA lesions that interfere with DNA metabolic processes such as replication, transcription, and recombination. USP11 deubiquitinase participates in DNA repair, but the role of USP11 in DPC repair is not known. SPRTN is a replication-coupled DNA-dependent meta...

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Detalles Bibliográficos
Autores principales:	Perry, Megan, Biegert, Meghan, Kollala, Sai Sundeep, Mallard, Halle, Su, Grace, Kodavati, Manohar, Kreiling, Natasha, Holbrook, Alexander, Ghosal, Gargi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960550/ https://www.ncbi.nlm.nih.gov/pubmed/33567341 http://dx.doi.org/10.1016/j.jbc.2021.100396

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