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AAV2-mediated and hypoxia response element-directed expression of bFGF in neural stem cells showed therapeutic effects on spinal cord injury in rats

Neural stem cell (NSCs) transplantation has been one of the hot topics in the repair of spinal cord injury (SCI). Fibroblast growth factor (FGF) is considered a promising nerve injury therapy after SCI. However, owing to a hostile hypoxia condition in SCI, there remains a challenging issue in implem...

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Detalles Bibliográficos
Autores principales: Zhu, Sipin, Ying, Yibo, Ye, Jiahui, Chen, Min, Wu, Qiuji, Dou, Haicheng, Ni, Wenfei, Xu, Huazi, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960741/
https://www.ncbi.nlm.nih.gov/pubmed/33723238
http://dx.doi.org/10.1038/s41419-021-03546-6