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AAV2-mediated and hypoxia response element-directed expression of bFGF in neural stem cells showed therapeutic effects on spinal cord injury in rats
Neural stem cell (NSCs) transplantation has been one of the hot topics in the repair of spinal cord injury (SCI). Fibroblast growth factor (FGF) is considered a promising nerve injury therapy after SCI. However, owing to a hostile hypoxia condition in SCI, there remains a challenging issue in implem...
Autores principales: | Zhu, Sipin, Ying, Yibo, Ye, Jiahui, Chen, Min, Wu, Qiuji, Dou, Haicheng, Ni, Wenfei, Xu, Huazi, Xu, Jiake |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960741/ https://www.ncbi.nlm.nih.gov/pubmed/33723238 http://dx.doi.org/10.1038/s41419-021-03546-6 |
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