Repurposing Treatment of Wernicke–Korsakoff Syndrome for Th-17 Cell Immune Storm Syndrome and Neurological Symptoms in COVID-19: Thiamine Efficacy and Safety, In-Vitro Evidence and Pharmacokinetic Profile

Coronavirus disease identified in 2019 (COVID-19) can be complicated by the Th17 cell-mediated IL-17 proinflammatory response. We tested if thiamine can effectively lower the Th17 response in a clinical study [Proinflammatory state in alcohol use disorder patients termed as disease controls (DC)] an...

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Detalles Bibliográficos
Autores principales: Vatsalya, Vatsalya, Li, Fengyuan, Frimodig, Jane, Gala, Khushboo S., Srivastava, Shweta, Kong, Maiying, Ramchandani, Vijay A., Feng, Wenke, Zhang, Xiang, McClain, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960760/
https://www.ncbi.nlm.nih.gov/pubmed/33737877
http://dx.doi.org/10.3389/fphar.2020.598128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960760/
https://www.ncbi.nlm.nih.gov/pubmed/33737877
http://dx.doi.org/10.3389/fphar.2020.598128

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