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Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma

A relevant fraction of castration-resistant prostate cancers (CRPC) evolve into fatal neuroendocrine (NEPC) tumors in resistance to androgen deprivation and/or inhibitors of androgen receptor pathway. Therefore, effective drugs against both CRPC and NEPC are needed. We have previously described a du...

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Detalles Bibliográficos
Autores principales: Sulsenti, Roberta, Frossi, Barbara, Bongiovanni, Lucia, Cancila, Valeria, Ostano, Paola, Fischetti, Irene, Enriquez, Claudia, Guana, Francesca, Chiorino, Giovanna, Tripodo, Claudio, Pucillo, Carlo E., Colombo, Mario P., Jachetti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960782/
https://www.ncbi.nlm.nih.gov/pubmed/33737929
http://dx.doi.org/10.3389/fimmu.2021.622001