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Impaired neurite development and mitochondrial dysfunction associated with calcium accumulation in dopaminergic neurons differentiated from the dental pulp stem cells of a patient with metatropic dysplasia

Transient receptor potential vanilloid member 4 (TRPV4) is a Ca(2+) permeable nonselective cation channel, and mutations in the TRPV4 gene cause congenital skeletal dysplasias and peripheral neuropathies. Although TRPV4 is widely expressed in the brain, few studies have assessed the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Kato, Hiroki, Sato, Hiroshi, Torio, Michiko, Han, Xu, Zhang, Yu, Hirofuji, Yuta, Kato, Takahiro A., Sakai, Yasunari, Ohga, Shouichi, Fukumoto, Satoshi, Masuda, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960789/
https://www.ncbi.nlm.nih.gov/pubmed/33748438
http://dx.doi.org/10.1016/j.bbrep.2021.100968