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The L1-dependant and Pol III transcribed Alu retrotransposon, from its discovery to innate immunity
The 300 bp dimeric repeats digestible by AluI were discovered in 1979. Since then, Alu were involved in the most fundamental epigenetic mechanisms, namely reprogramming, pluripotency, imprinting and mosaicism. These Alu encode a family of retrotransposons transcribed by the RNA Pol III machinery, no...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Netherlands
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960883/ https://www.ncbi.nlm.nih.gov/pubmed/33725281 http://dx.doi.org/10.1007/s11033-021-06258-4 |