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The zinc-binding domain of mammalian prolyl-tRNA synthetase is indispensable for catalytic activity and organism viability

Aminoacyl-tRNA synthetases (AARS) participate in decoding the genome by catalyzing conjugation of amino acids to their cognate tRNAs. During evolution, biochemical and environmental conditions markedly influenced the sequence and structure of the 20 AARSs, revealing adaptations dictating canonical a...

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Detalles Bibliográficos
Autores principales:	Vasu, Kommireddy, Ramachandiran, Iyappan, Terenzi, Fulvia, Khan, Debjit, China, Arnab, Khan, Krishnendu, Chechi, Aayushi, Baleanu-Gogonea, Camelia, Gogonea, Valentin, Fox, Paul L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960942/ https://www.ncbi.nlm.nih.gov/pubmed/33748704 http://dx.doi.org/10.1016/j.isci.2021.102215

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