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Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration

Chronic pancreatitis (CP) is characterized by a wide range of irreversible fibro-inflammatory diseases with largely ambiguous pathogenesis. Although neddylation pathway has been implicated in regulating immune responses, whether the dysregulation of neddylation is involved in the progression of CP a...

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Detalles Bibliográficos
Autores principales: Lin, Yuli, Chen, Yusheng, Feng, Wenxue, Hua, Rong, Zhang, Junfeng, Huo, Yanmiao, Jiang, Hong, Yin, Bo, Yang, Xuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960984/
https://www.ncbi.nlm.nih.gov/pubmed/33723230
http://dx.doi.org/10.1038/s41419-021-03549-3