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Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity
Phosphatases of regenerating liver (PRL1–3) are among the most oncogenic protein phosphatases but their mechanism of action is poorly understood. Multiple substrates have been proposed as well as a non-catalytic function regulating magnesium transport. Our recent identification of a catalytically in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960985/ https://www.ncbi.nlm.nih.gov/pubmed/33268817 http://dx.doi.org/10.1038/s41416-020-01194-9 |