Cargando…

Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity

Phosphatases of regenerating liver (PRL1–3) are among the most oncogenic protein phosphatases but their mechanism of action is poorly understood. Multiple substrates have been proposed as well as a non-catalytic function regulating magnesium transport. Our recent identification of a catalytically in...

Descripción completa

Detalles Bibliográficos
Autores principales: Gehring, Kalle, Miki, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960985/
https://www.ncbi.nlm.nih.gov/pubmed/33268817
http://dx.doi.org/10.1038/s41416-020-01194-9