Modeling preeclampsia using human induced pluripotent stem cells

Preeclampsia (PE) is a pregnancy-specific hypertensive disorder, affecting up to 10% of pregnancies worldwide. The primary etiology is considered to be abnormal development and function of placental cells called trophoblasts. We previously developed a two-step protocol for differentiation of human p...

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Detalles Bibliográficos
Autores principales: Horii, Mariko, Morey, Robert, Bui, Tony, Touma, Ojeni, Nelson, Katharine K., Cho, Hee-Young, Rishik, Hannah, Laurent, Louise C., Parast, Mana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961010/
https://www.ncbi.nlm.nih.gov/pubmed/33723311
http://dx.doi.org/10.1038/s41598-021-85230-5