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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers are urgently needed to identify patients who may benefit from such therapy. Here, we combine single-cell RNA-sequencing and multiparameter flow cytometry to a...

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Detalles Bibliográficos
Autores principales: De Biasi, Sara, Gibellini, Lara, Lo Tartaro, Domenico, Puccio, Simone, Rabacchi, Claudio, Mazza, Emilia M. C., Brummelman, Jolanda, Williams, Brandon, Kaihara, Kelly, Forcato, Mattia, Bicciato, Silvio, Pinti, Marcello, Depenni, Roberta, Sabbatini, Roberto, Longo, Caterina, Dominici, Massimo, Pellacani, Giovanni, Lugli, Enrico, Cossarizza, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961017/
https://www.ncbi.nlm.nih.gov/pubmed/33723257
http://dx.doi.org/10.1038/s41467-021-21928-4