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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy
Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers are urgently needed to identify patients who may benefit from such therapy. Here, we combine single-cell RNA-sequencing and multiparameter flow cytometry to a...
Autores principales: | De Biasi, Sara, Gibellini, Lara, Lo Tartaro, Domenico, Puccio, Simone, Rabacchi, Claudio, Mazza, Emilia M. C., Brummelman, Jolanda, Williams, Brandon, Kaihara, Kelly, Forcato, Mattia, Bicciato, Silvio, Pinti, Marcello, Depenni, Roberta, Sabbatini, Roberto, Longo, Caterina, Dominici, Massimo, Pellacani, Giovanni, Lugli, Enrico, Cossarizza, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961017/ https://www.ncbi.nlm.nih.gov/pubmed/33723257 http://dx.doi.org/10.1038/s41467-021-21928-4 |
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