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Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) is a chronic and severe psychiatric disorder for which effective treatment options are limited. Structural and functional neuroimaging studies have consistently implicated the orbitofrontal cortex (OFC) and striatum in the pathophysiology of the disorder. Recent g...

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Detalles Bibliográficos
Autores principales: Piantadosi, Sean C., McClain, Lora L., Klei, Lambertus, Wang, Jiebiao, Chamberlain, Brittany L., Springer, Sara A., Lewis, David A., Devlin, Bernie, Ahmari, Susanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961029/
https://www.ncbi.nlm.nih.gov/pubmed/33723209
http://dx.doi.org/10.1038/s41398-021-01290-1