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Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a chronic and severe psychiatric disorder for which effective treatment options are limited. Structural and functional neuroimaging studies have consistently implicated the orbitofrontal cortex (OFC) and striatum in the pathophysiology of the disorder. Recent g...
Autores principales: | Piantadosi, Sean C., McClain, Lora L., Klei, Lambertus, Wang, Jiebiao, Chamberlain, Brittany L., Springer, Sara A., Lewis, David A., Devlin, Bernie, Ahmari, Susanne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961029/ https://www.ncbi.nlm.nih.gov/pubmed/33723209 http://dx.doi.org/10.1038/s41398-021-01290-1 |
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