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Protectin DX restores Treg/T(h)17 cell balance in rheumatoid arthritis by inhibiting NLRP3 inflammasome via miR-20a
Regulatory T-cell (Treg)/T-helper 17 (T(h)17) cell balance plays an important role in the progression of rheumatoid arthritis (RA). Our study explored the protective effect of protectin DX (PDX), which restored Treg/T(h)17 cell balance in RA, and the role of the nucleotide-binding domain (NOD)–like...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961047/ https://www.ncbi.nlm.nih.gov/pubmed/33723242 http://dx.doi.org/10.1038/s41419-021-03562-6 |