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Protectin DX restores Treg/T(h)17 cell balance in rheumatoid arthritis by inhibiting NLRP3 inflammasome via miR-20a

Regulatory T-cell (Treg)/T-helper 17 (T(h)17) cell balance plays an important role in the progression of rheumatoid arthritis (RA). Our study explored the protective effect of protectin DX (PDX), which restored Treg/T(h)17 cell balance in RA, and the role of the nucleotide-binding domain (NOD)–like...

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Detalles Bibliográficos
Autores principales: Jin, Shengwei, Sun, Siyuan, Ling, Hanzhi, Ma, Jinglan, Zhang, Xu, Xie, Zhen, Zhan, Ning, Zheng, Wenjie, Li, Man, Qin, Yang, Zhao, Heping, Chen, Yan, Yang, Xinyu, Wang, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961047/
https://www.ncbi.nlm.nih.gov/pubmed/33723242
http://dx.doi.org/10.1038/s41419-021-03562-6