Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms

The seven 14-3-3 isoforms are highly abundant human proteins encoded by similar yet distinct genes. 14-3-3 proteins recognize phosphorylated motifs within numerous human and viral proteins. Here, we analyze by X-ray crystallography, fluorescence polarization, mutagenesis and fusicoccin-mediated modu...

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Detalles Bibliográficos
Autores principales: Gogl, Gergo, Tugaeva, Kristina V., Eberling, Pascal, Kostmann, Camille, Trave, Gilles, Sluchanko, Nikolai N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961048/
https://www.ncbi.nlm.nih.gov/pubmed/33723253
http://dx.doi.org/10.1038/s41467-021-21908-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961048/
https://www.ncbi.nlm.nih.gov/pubmed/33723253
http://dx.doi.org/10.1038/s41467-021-21908-8

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