Shc3 promotes hepatocellular carcinoma stemness and drug resistance by interacting with β-catenin to inhibit its ubiquitin degradation pathway

Hepatocellular carcinoma (HCC) is one of the most common cancers with an insidious onset, strong invasiveness, insensitivity to chemotherapy, and poor prognosis, thus makes clinical treatment challenging. The mechanisms require further elucidation for developing novel therapies and targeting drug re...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Zhuang, Hao, Cao, Fang, Li, Jie, Guo, Yan, Zhang, Jun, Zhao, Qiang, Liu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961052/
https://www.ncbi.nlm.nih.gov/pubmed/33723262
http://dx.doi.org/10.1038/s41419-021-03560-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961052/
https://www.ncbi.nlm.nih.gov/pubmed/33723262
http://dx.doi.org/10.1038/s41419-021-03560-8

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